Dr Golam Khandaker

Dr Golam Khandaker MBBS, MPhil, MRCPsych, PhD Lead, Inflammation and Psychiatry Research Group Wellcome Trust Fellow & Honorary Consultant Psychiatrist Department of Psychiatry, University of Cambridge Dr Khandaker is interested in the interactions between the immune system, brain and mind. Funded by the Wellcome Trust, his research group investigates novel immunological mechanism and treatment options for depression, schizophrenia and other psychiatric disorders. He is particularly interested in the role of low-grade inflammation (measured by cytokines, genes and peripheral immune cells). He uses population-based epidemiological cohort studies to examine causes and psychiatric consequences of inflammation, and clinical trials to examine the effect of novel immune-modulating drugs on cognition and mood. This work may help to inform more personalised approaches to treating major psychiatric disorders. Clinically, he has a special interest in the management of treatment resistant depression and depression in people with chronic inflammatory physical illness. Notable work includes cohort studies showing an association of depression with circulating interleukin 6 (IL-6) levels and with genetic variants known to regulate activity of IL-6, which indicate that the IL-6/IL-6R pathways may be causally linked to risk of depression. He received Young Investigator Awards from the International Early Psychosis Association (2014), the International Congress on Schizophrenia Research (2015), and was selected as a Rising Star in Psychiatry by the UK National Institute for Health Research (NIHR) in 2017.